Spironolactone and diabetic ketoacidosis.
نویسندگان
چکیده
Introduction Spironolactone is a specific competitive antagonist of aldosterone, the most potent endogenous mineralocorticoid, which modifies renal electrolyte handling and is therefore commonly used as a diuretic in conditions associated with secondary hyperaldosteronism. In renal insufficiency, aldosterone antagonists may induce significant hyperkalaemia even if administered concurrently with a thiazide.
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 57 671 شماره
صفحات -
تاریخ انتشار 1981